Taking your breath away…

I read quite a bit and love talking about it. Since beginning my postdoc, I read a lot about lung immunity, especially in the context of lung macrophages. I’ll use this space to have conversations about cutting edge findings about lung macrophages and immune memory.


I’ve started a thread of the coolest lung / macrophage papers I’ve read this year. You can follow along on bluesky app or Twitter app

20. Sina Bohnacker and Julia Esser-Von Bieren published a beautiful study about identifying key roles of heGDH in immune evasion, parasite chronicity, and tissue repair during helminth infections (Heligmosomoides polygyrus bakeri, Hpb).

Representative iF image for hegDh (green), cD64 (magenta), and DaPi (blue) in the small intestine from a mouse in-fected with Hpb (4 days). White arrows indicate colocalization of hegDh and macrophages in the surroundings of l4 larvae (dashed circle).

19. Nitschké and colleagues show that systemic or local blockade of Notch2 leads to an increase in pro-fibrotic lung macs.. affecting only recruited macs. RTMs do not seem to be the drivers of fibrosis!