Taking your breath away…
I read quite a bit of papers and love talking about it. I’d like to use this space to mostly highlight literature with undertones of immune memory and all it encompasses including the forces that coerce, maintain, dysregulate and incentivize immune memory.
2025
2. Dou Yu and Shuo Wang show that subcutaneous BCG vaccination induces MHCII+ ILC1 via TLR2 signaling, activate CD4+ T cells to promote anti-flu protection and immune response. Another evidence of skin:lung axis study.
1. Nargis Khan and Maz Divangahi show that β-glucan reprograms hematopoietic stem cells (HSC) in the bone marrow to generate ‘regulatory’ neutrophils which are required for promoting disease tolerance and lung tissue integrity against IAV challenge.
2024
21. Rebecca Dodd and Tara Sutherland identify IL-13 as a modulator of the Hyaluronan (HA) matrix during lung challenge. Using Nippostrongylus brasiliensis (Nb) model, authors link IL‐13‐mediated HA regulation to tissue repair pathways.
20. Sina Bohnacker and Julia Esser-Von Bieren published a beautiful study about identifying key roles of heGDH in immune evasion, parasite chronicity, and tissue repair during helminth infections (Heligmosomoides polygyrus bakeri, Hpb).
Representative iF image for hegDh (green), cD64 (magenta), and DaPi (blue) in the small intestine from a mouse in-fected with Hpb (4 days). White arrows indicate colocalization of hegDh and macrophages in the surroundings of l4 larvae (dashed circle).
